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, a Fairfield, New Jersey, accounting firm specializing in small-business finance
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. The House's protracted debate over the drug bill may have not produced much in the way of actual legislation, but it achieved its real goal: to convert Medicare into a Republican weapon in many close races
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. The major bottleneck to overcome in the design of efficient Monte Carlo simulations is the O(N^sup 2^) complexity associated with computing energies for each new conformation
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. These observations provide the necessary impetus for developing an accurate statistical thermodynamics framework for understanding how polypeptides respond to increasing concentrations of denaturants to yield ensembles that converge upon the EV limit description
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. Heterogeneous distribution and replication activity of mitochondria in Xenopus laevis oocytes
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. A further note of importance is that for the CPMG settings used, R^sub 2^(δ^sub 1^) is measured in the high ω^sub 1eff^ limit (ω^sub 1eff^ > p^sub A^Δω^sub I^), so that R^sub ex^ is proportional to B^sup 2^^sub o^ independent of whether the exchange is fast or slow to a skewed population (33,34)
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. In conclusion, residues with fast exchange can be identified from the combination of R^sub ex^ and ΔR^sub ex^ using either the fast exchange equations or the general fast/slow exchange equations derived by Ishima and Torchia (34)
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. Rotational-dynamics of calcium-free calmodulin studied by ^sup 15^N NMR relaxation measurements
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. Heat-induced gelation of globular proteins
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. Cross-linking was allowed to proceed for 120 s before quenching by addition of 10 µl of 7% NaBH^sub 4^ in 0
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. The majority of mature amyloids are unbranched fibrils (Rochet and Lansbury, 2000) consisting of several, often intertwined protofilaments (which may form an internal waterfilled canal-Perutz et al
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. Conversely, pellets maintained in DMEM/10%FCS possessed limited extracellular matrix (Fig
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. --Pharmaceutical Sciences Social and Administrative SciencesSOURCE: AMERICAN ASSOCIATION OF COLLEGES OF PHARMACY <WWW
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. Bruce Roberts, executive vice president and chief executive officer of the National Community Pharmacists Association, echoed that call to action
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. A further note of importance is that for the CPMG settings used, R^sub 2^(δ^sub 1^) is measured in the high ω^sub 1eff^ limit (ω^sub 1eff^ > p^sub A^Δω^sub I^), so that R^sub ex^ is proportional to B^sup 2^^sub o^ independent of whether the exchange is fast or slow to a skewed population (33,34)
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. Furthermore, several residues in CaM also undergo conformational exchange on a timescale of ~50 µs
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. We find that the K^sub d^ value for this interaction in solution is higher than expected based on a simple model where we calculate protein association on the reduced volume of the membrane
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