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. These results indicate a multistate folding pathway for GR and suggest a critical role of molten globule monomers in the correct dimerization of GR
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. Therefore, the K^sub SV^ of 40 M^sup -1^ obtained for iodide quenching of GR in the presence of 7 M GdnHCl suggests that the Trp residues of the protein are significantly, if not completely, exposed to the solvent
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. The changes of thermodynamic parameters (enthalpy change ((Delta)H), entropy change ((Delta)S) and heat capacity change ((delta)C^sub p^)) corresponding to the transitions from N to MG (molten globule state) or MG to U (unfolded state), were summarized in the previous report (Nishii et al
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. The rSBA clone that was in the pET 11b vector was transformed into Escherichia coli BL21 DE3 pLysS cells
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. The biological relevance of the partially folded species at acidic pH is unknown, and we do not know whether the residual secondary structure detected by CD and FTIR (Table 2) was native-like
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. Study of the "molten globule" intermediate state in protein folding by a hydrophobic fluorescent probe
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. Future treatments, such as small molecule chemotherapy, are viable strategies, and early diagnosis to enable initiation of this therapy at an early stage is vital
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. Self-association of human apolipoproteins A-I and A-II and interactions of apolipoprotein A-I with bile salts: quasi-elastic light scattering studies
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. In striking contrast, neither the 2WJ nor the 3WJ ribozymes can populate such a high-FRET state in the absence of loop A
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. (1,8) Both victims and shooters are typically male (90% of cases), and most of these injuries occur while the children are playing unsupervised (90%) at home (60 to 75%)
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. "Wal-Mart also continues to work with its vendors-including its pharmaceutical suppliers--to adopt radio frequency identification in all product shipments
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. The absence of a long native baseline at this and other pH in EI^sup sc^ precluded any reliable conclusion on the pH independence of this value of T^sub m^
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. The N-H^sup N^ bond length was set to 1
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