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Representative isothermal and thermal denaturation profiles show that glycosylation accounts for a stabilization of ~9 kcal/mol of the tetramer, whereas the difference in T^sub m^ between the two forms is 26°C
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In many instances, glycosylation is seen to have a remarkable effect in attaining the final functional fold of the protein, whereas in others it is seen to have little or no effect on the ultimate state of the protein
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